Guidance for Reimbursement and Support

Find downloadable forms, online resources, reimbursement information and hematology knowledge in one place.

Hematology Support Center

The Hematology Support Center (HSC) is a full-service support hotline designed to assist patients and their providers and staff with reimbursement challenges, treatment access, education requests and other general inquiries about Shire's hematology products.

Our knowledgeable Case Managers provide:
  • Live Answers
  • Benefits Verification Assistance
  • Prior Authorization Assistance
  • Appeals Support
  • Billing and Coding Expertise
  • Resources, Checklists and Templates

Contact us at 1-855-229-7377.
Mon – Fri | 8:30 a.m. to 8:00 p.m. ET

Fax Number: 1-866-467-7740

Product Information

Find brand-specific information related to reimbursement plus links to product support.

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Find a Shire Rep

Connect with your local Shire representative to get the answers to any questions you may have.

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Reimbursement Resources

Download these helpful tools to ensure your patients receive the treatment you recommend.

Patient Consent Form

Download HSC's Patient Consent form, complete and fax to 1-866-467-7740.


Prior Authorization Checklist

Follow this simple checklist and take the guesswork out of prior authorization and reauthorization paperwork.


Appeals Reference Guide

A checklist of supporting documents to help prepare your patient's appeal.


Letter of Medical Necessity (LMN)

A template that can be customized based on your patient's medical history and information to support medical necessity.


Patient Support Programs

These links provide additional resources that may be invaluable for both you and your patients.

CoPay Assistance

Your patients may be eligible to receive up to $12,000 in CoPay support with Shire's CoPay Assistance Program.

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Free Trial Program

Find out if your patients are eligible to receive free doses of their treatment regimens through our FREEDOM OF CHOICE program.

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Resource Library

These links are invaluable in helping you and your patients navigate the hematology and insurance landscape.

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Patients denied coverage from a commercial health insurance plan for select hematology products may be eligible for up to 12 months of free medication.

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Hematology Support for Your Patients

Help your patients access information on patient assistance, insurance options and healthcare reform with customizable tools and resources at

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